Samuel Howe was born 14 October 1654 in Concord, Middlesex County, Massachusetts to William Howe (1616-1675) and Mary Farmer (1631-1695) and died 29 December 1724 Plainfield, Windham County, Connecticut of unspecified causes. He married Mary Nutting (1656-1727) 26 March 1678 in Concord, Middlesex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Mary Howe (1676-1761) | |||
| Sarah Howe (1677-1678) | |||
| Samuel Howe (1679-1755) | |||
| Sarah Howe (1679-1760) | |||
| Mary Howe (1682-1749) | |||
| Hannah Howe (1683-1683) | |||
| Deborah Howe (1685-1748) | 19 October 1685 Concord, Middlesex County, Massachusetts | 1 September 1748 Canterbury, Windham County, Connecticut | David Munroe (1680-1755) |
| John Howe (1689-1727) | |||
| Abigail Howe (1692-1774) | |||
| Elizabeth Howe (1694-) | |||
Siblings
| Name | Birth | Death | Joined with |
| Samuel Howe (1654-1724) | 14 October 1654 Concord, Middlesex County, Massachusetts | 29 December 1724 Plainfield, Windham County, Connecticut | Mary Nutting (1656-1727) |
| Daniel Howe (1656-1657) | |||
| Sarah Howe (1658-1659) | |||
| Hannah Howe (1660-1683) | |||
| William Howe (1663-1663) | |||
| Mary Howe (1665-1666) | |||