Louisa Bigelow Howe was born 9 September 1806 in Marlborough, Middlesex County, Massachusetts to Gershom Bigelow (1768-1847) and Mary Howe (1769-1820) and died 18 January 1862 Massachusetts of unspecified causes. She married Eber Howe (1795-1872) 16 September 1824 in Marlborough, Middlesex County, Massachusetts.
Children
| Name | Birth | Death | Joined with |
| Mary Howe (1824-1875) | |||
| Lucy B Howe (1825-1916) | |||
| Silas Howe (1828-1907) | 17 January 1828 Marlborough, Middlesex County, Massachusetts | 21 March 1907 Massachusetts | Ann Gilmore Snell (1828-1917) |
| Augusta Howe (1830-1854) | |||
| Lydia Howe (1832-1852) | |||
| Everett Howe (1836-1837) | |||
| Cordelia B Howe (1838-) | |||
| Edward Howe (1841-1843) | |||
| Louisa Annie Howe (1844-) | |||
Siblings
| Name | Birth | Death | Joined with |
| Lydia Bigelow (1788-1840) | |||
| Levi Bigelow (1790-1859) | |||
| Lucinda Bigelow (1792-1850) | |||
| Lyman Bigelow (1795-1842) | |||
| Patricia Bigelow (1797-1819) | |||
| Mary Bigelow (1799-1818) | |||
| Lambert Bigelow (1801-1863) | |||
| Lewis Bigelow (1804-1849) | |||
| Lewis Bigelow (1804-1849) | |||
| Louisa Bigelow (1806-1862) | 9 September 1806 Marlborough, Middlesex County, Massachusetts | 18 January 1862 Massachusetts | Eber Howe (1795-1872) |
| Lucas Bigelow (1808-1851) | |||
| Lucy Bigelow (1811-1874) | |||
| Name | Birth | Death | Joined with |
| Charles Dana Bigelow (1823-1883) | |||
| Gershom Palifaux Bigelow (1824-1865) | |||
| John Bigelow (1826-1849) | |||
| Mary August Bigelow (1828-1915) | |||
| Walter Balfour Bigelow (1831-) | |||