James Bigelow was born 17 May 1722 in Weston, Middlesex County, Massachusetts, United States to Jonathan Bigelow (1679-1745) and Elizabeth Bemis (1681-1734) . He married Sarah Bigelow (c1725-) 1740 in Weston, Middlesex County, Massachusetts.
|Offspring of James Bigelow and Sarah Bigelow (c1725-)|
|James Bigelow (1742-1829)|
|Enoch Bigelow (1746-1780)||2 October 1746 Worcester, Worcester County, Massachusetts||1780||Elizabeth Clemons (1747-1823)|