Friederike Charlotte Ulrike Katharina von Preußen was born 7 May 1767 in Potsdam, Brandenburg, Germany to Friedrich Wilhelm II. von Preußen (1744-1797) and Elisabeth Christine Ulrike von Braunschweig-Wolfenbüttel (1746-1840) and died 6 August 1820 Oatlands Park Weybridge, Surrey, England, United Kingdom of unspecified causes. She married Frederick, Duke of York and Albany (1763-1827) 28 September 1791 in Berlin, Germany. Charlemagne (747-814)/s, Henry II of England (1133-1189)/s, Willem van Oranje (1533-1584)/s, Hugh Capet (c940-996)/s, Gustav I of Sweden (1496-1560)/s, Robert I of Scotland (1274-1329)/s.
The new Duchess of York received an enthusiastic welcome in London, but the marriage was not a happy one. The couple soon separated and the Duchess retired to Oatlands Park, Weybridge, where she lived eccentrically and died in 1820. Their relationship after separation appears to have been amicable, but there was never any question of reconciliation. They had no children.