Francis Willoughby, 5th Baron Willoughby of Parham, was born circa 1614 to William Willoughby, 3rd Baron Willoughby (1584-1617) and Frances Manners (1588-1643) and died 23 July 1666 of unspecified causes. He married Elizabeth Cecil (c1606-1661) 16 November 1628 .
|Offspring of Francis Willoughby, 5th Baron Willoughby of Parham and Elizabeth Cecil (c1606-1661)|
|Diana Willoughby (c1628-1648)|
|Robert Willoughby (1629-1630)|
|Frances Willoughby (-1680)|
|Elizabeth Willoughby (-1695)||1 August 1695 Chelsea, Greater London, England, United Kingdom||Richard Jones, 1st Earl of Ranelagh (1641-1712)|
|William Willoughby (bef1639-1661)|