Flora Sheldon was born 17 March 1872 in Franklin County, Ohio, United States to Robert Emmet Sheldon (1845-1917) and Mary Elizabeth Butler (1850-1897) and died 4 September 1920 "Watch Hill" Road, Westerly, Rhode Island, United States of being hit by a car. She married Samuel Prescott Bush (1863-1948) 1 June 1894 in Columbus, Franklin County, Ohio, United States.
|Offspring of Samuel Prescott Bush and Florence Sheldon (1872-1920)|
|Prescott Sheldon Bush (1895-1972)||15 May 1895 Columbus, Franklin County, Ohio, United States||8 October 1972 New York City, New York, United States||Dorothy Wear Walker (1901-1992)|
|Robert Sheldon Bush (1896-1900)||20 November 1869 Columbus, Ohio, United States||28 March 1900 Milwaukee, Wisconsin, United States|
|Mary Eleanor Bush (1898-1992)||18 December 1897 Columbus, Franklin County, Ohio, United States||20 December 1992 Meriden, New Haven County, Connecticut, United States||Francis Edwin House (1889-1971)|
|Margaret Livingston Bush (1899-1993)|
|James Smith Bush (1901-1978)|
Grandmother of President George H. W. Bush. Through her mother, Flora descended from four Mayflower passengers.