Abbott family
- Simon Abbott (-)
- Dorcas Abbott (-)
Adams family
- Francis Adams (-)
- John Adams (-)
- Charles Adams (-)
Alford family
- Moses Alford (-c1708)
- Aaron Alford (living in 1738-)
- Moses Alford, (-c1733)
Alley family
- John Alley (living in 1730-)
- John Alley (living in 1756-)
Ambrose family
- Abraham Ambrose (-c1738)
- Abraham Ambrose, Jr. (-c1758)
- Thomas Ambrose (1700/01-c1740)
- John Ambrose (1710-), planter
- John Ambrose, Jr. (bap1727--)
Andrews family
- Samuel Andrews (living in 1727-), schoolmaster
- Christopher Andrews (-c1677)
- John Andrews (living in 1760-)
- Martha Andrews (-), named in her daughter's will on 19 Sep 1743
Bowie family
- John Bowie, Sr (1688-1759), land owner
- Gov. Oden Bowie (1828-1894), 34th Governor of Maryland, Maryland State Senator
- Gov. Robert Bowie (1750-1818), Governor of Maryland, Member of the Maryland House of Delegates
- Hon. Thomas Fielder Bowie (1808-1869), Member of the U.S. House of Representatives from Maryland's 6th district, Member of the Maryland House of Delegates
- Hon. Walter Bowie (1748-1810), Member of the Maryland House of Delegates, Maryland State Senator
- Capt. Hon. William Bowie (1721-), Member of the Assembly of Freeman, delegate to the Annapolis Convention of (1774-1776)
- Hon. William Duckett Bowie (1803-1873), Member of the Maryland House of Delegates, member of the Levy Court of Prince George's County
Bozman family
- John Bozman (1650-1716), arrived from Accomack County, VA
- George Bozman (1682-1760)
- Ann Bozman (1705-1748)
Brent family
- Margaret Brent (c1601-c1671)
- Mary Brent (-)
- Giles Brent (-)
- Fulke Brent (-)
Brice family
- John Brice, Jr. (1705-1766)
- Hon. John Brice III (1738-1820), Mayor of Annapolis, lawyer, businessman and political leader
- Gov. James Brice (1746-1801), Governor of Maryland, Mayor of Annapolis, Maryland
Brooke family
- Gov. Robert Brooke, Sr. (1602-1655), Governor of Maryland for three months
- Maj. Thomas Brooke, Sr. (1632-1676), Member of the House of Burgess, High Sheriff and Chief Justice
- Col. Thomas Brook, Jr. (1659-c1630), 2 degree Governor of Restored Proprietary Government
Calvert family
- George Calvert (1579-1632), 1st Baron Baltimore
- Cecil Calvert (1605-1675), 2nd Baron Baltimore
- Leonard Calvert (1606-1647), Governor of the Maryland Colony
- Philip Clavert (1626-1682), Governor of the Maryland Colony
- Charles Calvert (1637-1715), 3rd Baron Baltimore
- Benedict Calvert (1679-1715), 4th Baron Baltimore
- Charles Calvert (1699-1751), 5th Baron Baltimore, FRS
- Benedict Leonard Calvert (1700-1732), 15th Proprietary Governer of Maryland
- Benedict Swingate Calvert (1722-1788), 3rd Proprietary Govery of Maryland
- Frederick Calvert (1731-1771), 6th Baron Baltimore
- Henry Harford (1758-1835), 5th Proprietary Governor of Maryland
- Chalres Benedict Calvert (1808-1864), Member of the Maryland House of Deleagtes
- Capt. Charles Calvert (1688-1734), 14th Proprietary Governor of Maryland
Carroll family
- Hon. Charles Carroll the Settler (1661-1720), Attorney General of the Maryland Colony
- Charles Carroll II of Annapolis (1702-1782)
- Hon. Charles Carroll (1723-1783) (barrister)
- Hon. Charles Carroll of Carrollton (1737-1832), United States Senator form Maryland
- Hon. Daniel Carroll (1730-1796), Member of the U.S. House of Representatives from Maryland's 6th district
- The Most Reverend John Carroll, SJ (1735-1815), Archbishop of Baltimore
- Hon. John Lee Carroll (1830-1911), 37th Governor of Maryland, Maryland State Senate
- Col. Henry James Carroll (-)
- Thomas King Carroll (1793-1873), 21st Governor of Maryland
- Anna Ella Carroll (1815-1894), politician
- Hon. James Carroll (1791-1873), Judge of the orphan's court and a trustee of the poor, Director of the Baltimore & Ohio Railroad and the Chesapeake & Ohio Canal Company
- Brevet Maj. Gen. Samuel Sprigg "Red" Carroll ( 1832-1893), Commander of the 8th Ohio Infantry, fought in the Battle of Gettysburg
Chaplin family
- William Chaplin (1625-1669), planter, juror, proprietor of three hundred acres of land on Hooper's Island; his father was Capt. Isaac Chaplin of the British Royal Navy and arrived in Virginia in 1608.
- William Chaplin, Jr. (1659-1718), inherited his father's plantation, juror
- Mary Chaplin (1663-)
- Isaac Chaplin (-1743)
- Solomon Chaplin (-1765)
- Thomas Chaplin (-1730)
- Mary Chaplin (-)
- Elizabeth Chaplin (-)
Cullen family
- George Cullen (1650-1683)
- John Cullen (1674-1718)
- Thomas Tyler (c1718-1812)
- Mary Tyler (c1738-)
Daugherty family
- Nathaniel Daugherty (c1630-1703)
- Nathaniel Daugherty (1650-1687)
- John Daugherty (c1683-1757)
- Isaac Daugherty (c1733-c1762)
- Rachel Daugherty (1762-)
Dickerson family
- Edward Dickerson (1627-1682), Gent., immigrant
- Elizabeth Dickerson (1644-1733)
- John Dickerson (1662-)
- Peter Dickerson (1664-1733)
- Edward Dickerson, Jr. (1666-)
- Mary Dickerson (1673-)
Hooper family
- Capt. Henry Hooper I (c1600-1649), immigrant, Captain of the Calvert County Militia, Gentlemen Justice of the Peace for Calvert County, a first settler of Hooper's Island
- Elizabeth Hooper (c1622-1646)
- Mary Hooper (bet1625/1633-bet1663/1665)
- Alice Hooper (c1630-1703)
- Richard Hooper (1640-1673)
- Unknown Person (-)
- Henry Hooper, Jr. (-1676)
Horsey family
- Stephen Horsey (1620-1671), immigrant, rebel
- Col. Isaac Horsey (1665-1752)
- Sarah Horsey (1689-1723)
Lawson family
- Rev. Robert Lawson (c1665-bef1713)
- Samuel Lawson (c1680-bef1756)
- Hance Lawson (1700-aft1746)
- Samuel Lawson (c1723-aft1788)
London family
- Maj. Hon. Ambrose London (c1618-1706, immigrant, planter, Justice of the Peace, elected to the Lower House of Maryland General Assembly
- Mary London (1644-1730)
- Thomas London (1647-1662/63)
- Ruth London (1657-)
- Abigail London (1660-1692)
Martin family
- Francis Martin (c1658-1699), he panted 150 acres of land
- Mathew Martin (1684-1684)
- Mary Martin (1687-1748)
- Sarah Martin (1689-)
- Frances Martin (1691-), he was proprietor of 345 acres and owner of "Parker's Place"
- John Martin (1693-)
- Martha Martin (1695-)
Minshall family
- Jeffrey Minshall I (1620-1675), immigrant, owner of 400 acres called "Adventures" at the head of Marumsco Creek
- Ann Minshall (c1666-)
Moore family
- Richard Moore (1625-1676), immigrant from Ireland
- John Moore (c1660-1717)
- Thomas Moore (c1678-1721)
- Isaac Moore I (c1707-1771)
- Isaac Moore II (c1736-aft1810)
Roach family
- John Roach I (1635-1718), immigrant, proprietor of 757 acres
- John Roach, Jr. (1663-1727)
- Sarah Roach (1666-1709)
- Mary Roach (1669-1709)
- Elizabeth Roach (1670-)
- Abigail Roach (1673-)
- William Roach (1675-1687)
- Arabella Roach (1679-)
- Nathaniel Roach (1681-1721)
- Michael Roach (1683-1720)
- Hannah Roach (1687-)
- Joseph Roach (1689-)
- Samuel Roach (1692-1736)
Riggin family
- Teague Riggin I (c1640-1707), immigrant and proprietor of 1,000 acres in Maryland
- Mary Riggin (1667/68-)
- Teague Riggin III (1670-1721/22)
- Ambrose Riggin (1673-)
- Sarah Riggin (1676-c1743)
- Ruth Riggin (1677/78-)
- John Riggin (c1680-), planter
- Darby Riggin (1683-), planter
- Rachel Riggin (1686-)
- Samuel Riggin (1689-)
Schoolfield
- George Schoolfield (1741-1798)
- Isaac Bozeman Schoolfield (1775-1847)
Sterling family
- John Sterling I (1641-1705)
- John Sterling, Jr. (1676-1741)
- John Sterling III (1700-1779)
- Travers Sterling (1740-1836)
- Aaron "Crow" Sterling (1792-1871), farmer
- David "Twister" Sterling (1825-1906)
- Nancy Isabella Sterling (1848-1917)
- Mary Sterling (1850-1928)
- Matilda "Tillie" Sterling (1852-1924)
- William J. Sterling (1855-1932)
- Virginia Sterling (1857-)
- Alice Sterling (1857-1908)
- Annie R. Sterling (1862-1925)
- Georgia Sterling (1867-1937)
Travers family
- William Travers I c1642-1700), immigrant from Ireland, Justice of the Calvert County Court and the Dorchester County Court
- William Travers (1684-1730)
- Mary Travers (1710-1777)
Tyler family
- John Tyler, Jr. (1686-1734/35), Henry Smith sold 200 acres of land to him and he was one of the two people that bought land from Henry Smith. John and another person were the first two settlers in Smith Island, Somerset County, Maryland.
- Richard Tyler (1692-aft.1733
- John Tyler (1693-1693/94)
- John Tyler (1694-bef.1778)
- Aldon Tyler (c.1701-)
- Else Tyler (c.1702-aft.1733)
- Thomas Tyler (c1708-1812)
- Mary Tyler (c1738-)
Ward family
- Cornelius Ward I (c1639-1722/23), immigrant, a first settler of Somerset County, Maryland, proprietor of 1,375 acres, and owner of Bear Point, Cork, Long Acres and White Oak Swamp, Justice of the Peace
- John Ward (1667/68-aft1736)
- Alice Ward (1665-1687)
- Cornelius Ward, Jr. (1670-1736)
- William Ward (1672/73-1716)
- Thomas Ward (1672-aft1717)
- Margaret Ward (1678-aft1772)
- Samuel Ward (1684-1761)
- Stephen Ward (af1686-1736)
- Jonathan Ward (aft1686-aft1736)
- Catherine Ward (aft1686-aft1722)
- Josephen Ward (1688-1765)
- Samuel Ward (1684-1761)
- Martha Ward (c1730-1761)
Wilson family
- Abraham Wilson (1761-1801)
- Abraham Wilson, Jr. (1801-bef1850)
- Elijah Thomas Wilson (1818-bef1860)
- Capt. John Moses Ewing Wilson (1851-1900)