Descendants of Cosimo I de Medici

Descendants in three generations

Cosimo I de ' Medici 80px Grand duke of Tuscany See Ancestors	Children	Grand Children	Great-Grand Children
	Francesco I de' Medici Grand duke of Tuscany See Descendants	Marie de' Medici Queen of France See Descendants	Henriette-Marie de Bourbon Princess of France Queen Consort of England, Scotland and Ireland See Descendants
			Louis XIII of France King of France
			Elisabeth of Bourbon Queen of Spain
			Christine Marie of France Regent of Savoy
			Gaston Jean-Baptiste Duke of Orléans
		Eleonora di Medici	Francesco IV Gonzaga
			Ferdinando I Gonzaga
			Vincenzo II Gonzaga
	Ferdinando I de' Medici Grand duke of Tuscany See Descendants	Cosimo II de' Medici Grand duke of Tuscany See Descendants	Ferdinando II de' Medici Grand duke of Tuscany See Descendants
			Maria Cristina (August 24, 1609 - August 9, 1632)
			Giancarlo (July 24, 1611 - January 23, 1663), Cardinal
			Margherita (May 31, 1612 - February 6, 1679)
			Mattia (April 9, 1613 - October 14, 1667)
			Francesco (October 16, 1614 - July 25, 1634)
			Anna (July 21, 1616 - September 11, 1676)
			Leopoldo (November 6, 1617 - November 10, 1675), Cardinal
	Isabella de' Medici Princess See Descendants	Virgino Orsini	Ferdinando Orsini,
			Alessandro di Virginio Orsini,
			Paolo Giordano II Orsini,
			Francesco Orsini,
	Bia di Cosimo I de' Medici b.1537 d.1542	End of Line
	Maria di Cosimo I de' Medici 80px b.1540 d.1557	End of Line
	Giovanni di Cosimo I de' Medici, b.1543 d.1562	End of Line
	Lucrezia di Cosimo de' Medici 80px Duchess	End of Line
	Garzia di Cosimo I de' Medici, b.1547 July 5 d.1562 December 12	NN	NN
	Pietro di Cosimo I de' Medici, b.1554 June 3 d.1604 April 25	NN	NN
	Giovanni di Cosimo I de' Medici, b.1567 May 13 d.1621 July 19	Gianfrancesco Maria di Giovanni de' Medici	NN
	Virginia di Cosimo I de' Medici, b.1568 May 28 d.1615 January 15	Alfonso III d' (fra Giambattista da Modena)	Margherita d' Este-Gonzaga di Guastalla, d.1692 November 12
			Anna Beatrice d' Este-Pico della Mirandola, d.1690 September 25
			Cesare di Alfonso III d' Este, b.1609 d.1613
			Francesco I d' Este, b.1610 September 6 d.1658 October 14
			Obizzo di Alfonso III d' Este, b.1612 d.1645
			Caterina di Alfonso III d' Este, b.1613 d.1628 January 26
			Cesare di Alfonso III d' Este, b.1614 d.1677
			Rinaldo di Alfonso III d' Este, (Cardinale) b.1618 d.1672 September 30
			Filiberto di Alfonso III d' Este, b.1623 d.1645