Born in 1749

• Bethany Arnold (1749-1844)

• Nicholas Bayly (c1749-1814)
• Simon Beers (1749-1828)
• John Benson (1749-1818)
• Georgiana Augusta Berkeley (1749-1820)
• François Bertrand (1749-1813)
• William Bigelow (1749-1813)
• Mary Eleanor Bowes (1749-1800)
• Thomas Brand (1749-1794)
• John Brewer (1749-1836)
• Aaron Browne (1749-1840)
• Thomas Bruce (c1749-1820)
• Carsten Burfeind (1749-1752)
• James Butler (c1749-1829)

• Martha Chapman (1749-1782)
• John Chester (1749-1809)
• Jan Nepomuk Rudolf Chotek von Chotkov und Vojnín (1749-1824)
• Job Clevenger (1749-1772)
• John Cotes (1749-1821)
• Jacqueline Coyne (1749-1830)
• Mary Crosby (1749-1823)

• Oene Geerts Dolstra (1749-1809)
• Ocy Doty (c1749-1830)
• Silas Doty (1749-1824)
• Edward George Dougherty (1749-1814)
• Annah Draper (1749-1802)

• Hendrick Eldert (1749-1793)

• William Robert FitzGerald, 2nd Duke of Leinster (1749-1804)

• Helen Grant (c1749-1827)
• Pieter Grooteman (1749-1811)

• Rufus Harris (1749-1798)
• Joseph Howland (1749-1836)
• John Hull (c1748-1836)
• Hannah Huntington (1749-1829)
• Samuel Hutchinson (1749-1821)
• Abiah Hyde (1749-1788)

• Edward Jenner (1749-1823)

• Dmitri Konstantinovich Kantemir (1749-1820)
• John Kellock (1749-1816)
• Steven Kieft (c1749-1821)

• Alexander Leslie-Melville, 9th Earl of Leven (1749-1820)
• Henry George Liddell, 5th Bart (1749-1791)
• Lydia Loomis (1749-1775)
• Catherine Lovewell (1749-1794)
• Joseph Lyman (1749-1828)

• Thomas Manning (1749-1825)
• Barnabas Matthews (1749-1826)
• David McKeen (1749-1830)
• Louisa Molesworth (1749-1824)
• David Mosher (1749-1797)

• Daniel Newton (1749-1831)
• Mary Norman (1749-1815)
• Sally Nurse (1749-1799)

• Christian VII of Denmark (1749-1808)

• Levi Phelps (1749-1829)
• John Pulsipher (1749-1827)
• Mehitabel Putnam (1749-1789)
• Borbála Péchy (1749-1785)

• Rhoda Rawson (1749-1827)
• Frances Elizabeth Reynardson (c1749-)
• Mary Rice (1749-1832)
• 
  Jonathan Risley (1749-1813)
• Thomas Rose (c1749-1833)
• Lois Rowley (1749-1783)

• Jan Schaper (c1749-1807)
• Oliver Snow (1749-1841)
• 
  Olive Soule (1749-1833)
• 
  Jane Strand (1749-1805)
• John Sullivan (1749-1839)
• Nathaniel Swift, Jr. (1749-1825)
• Ruthea Swinney (1749-1830)
• Erzsébet Szemere (1749-1806)

• John Talbot (1749-1793)
• Crelis Tol (1749-1804)
• Teunis Tuin (1749-1803)

• Annetje Jordens van de Meent (bef1749)
• Cornelis Jansz van Raaphorst (1749-)
• Johann Wolfgang von Goethe (1749-1832)

• William Walker (1749-1790)
• Krelis Weel (1749-)
• Henry Perkins Weston (1748-1826)
• Timothy Weston (1749-1783)
• John Wildish (1749-1818)
• Jacob Winegar (1749-1810)
• Joshua Winsor (1749-1827)
• 
  Eldad Woodruff (1749-1805)
• Giffey Wyatt (1749-1814)