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Roman Empire

 * A Roman military operation under is successful against, capturing , , and .  The Parthians sue for peace.
 * A known as the  breaks out in Rome after the  returns from .  The plague significantly depopulates the empire.
 * is levied by.
 * The Romans establish a garrison at Doura Europos on the, a control point for the commercial route to the.
 * Avidius Cassius takes and conquers the north of.
 * Marcus Aurelius creates four legal districts (iuridici) in Italy (5 if Rome is included).

Religion

 * The philosopher of Nablus is executed in Rome as a.
 * Discourse to the Greek (Oratio ad Graecos), by the, is the first treatise on the evils of paganism in Christian literature.

Births

 * , (approximate date)

Deaths

 * , early apologist for
 * , Greek astronomer (approximate date)