250

Roman Empire

 * A group of penetrate as far as  in Spain (approximate date).
 * The invade.
 * The drive the Romans from the modern area of.
 * An epidemic of the begins in  and spreads through the Roman Empire.

Africa

 * The Kingdom of  takes control of commerce on the.

Asia

 * The begins in.
 * The Empire collapses.

The Americas

 * is rebuilt as a four-quartered cosmogram by architects brought from  in.

Arts and Sciences

 * writes Arithmetica, the first systematic treatise on algebra.

Births

 * ,  (approximate date)
 * , Roman emperor, (approximate date)
 * , Roman emperor and father of (approximate date)
 * , Roman emperor (approximate date)
 * ,  and founder of  (approximate date)

Deaths

 * , Christian writer (approximate date)
 * , founder of ("Great Vehicle")
 * , general of
 * , general of
 * , general of
 * , general of