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2,6-diaryl pyridazinones with immunosuppressant activity Richard Arthur Norton (1958- ) on February 23, 1995

Abstract: A class of 2,6-diarylpyridazinones of general structural formula I have been identified that exhibit exhibit immunosuppressant activity with human T-lymphocytes, and are useful as an immunosuppressants. [Structure] or a pharmaceutically acceptable salt, hydrate or crystal form thereof, wherein:

Patent number: 5506228 Filing date: Feb 23, 1995 Issue date: Apr 9, 1996 Inventors: Richard Norton, Mohammed K. A. Ibraham Assignee: Merck & Co., Inc.

U.S. Classification: 514/247; 544/240 International Classification: A61K 3150