1516

Year 1516 was a  (link will display the full calendar) of the.

January - June

 * March - With the death of, his grandson becomes King of Spain as Carlos I.
 * - The is instituted in,  regulating the purity of  permissible for sale.

July - December



 * July - of the  declares war on the  and invades Syria.
 * - The is signed.   recognizes Charles's claim to Naples, and Charles recognizes Francis's claim to Milan.
 * - . Turkish forces under the Grand Vizier Sinan Pasha defeat the Mameluks near.
 * - - Peace between France and the Empire.

Undated

 * discovers the.
 * King and  sign the.
 * publishes a new translation of the.
 * publishes .

Births

 * -, queen of (died )
 * - Queen (died )
 * -, Swiss naturalist (died )
 * -, Protestant German poet (died )
 * - (died )
 * date unknown
 * , biographer (died )
 * , Silesian cartographer (died )
 * , ruler of the Inca (died )
 * , khan of Qasim and Kazan
 * , son of.
 * probable
 * (died )


 * See also .

Deaths

 * -, Spanish navigator and explorer (born )
 * - King (born )
 * -, ruler of Florence (born )
 * -, English diplomat (born )
 * - King (born )
 * - King (born )
 * August -, Dutch painter (born )
 * -, German scholar and cryptographer (born )
 * date unknown
 * , Italian sculptor and architect (born )
 * probable
 * , Italian painter (born )


 * See also .