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Method for inhibiting activation of the human A3 adenosine receptor to treat asthma

Abstract The invention is a method for inhibiting activation of the human A3 adenosine receptor with adenosine, by treating the receptor a compound of the formula ##STR1## to treat asthma.

Patent number: 5780481 Filing date: Aug 8, 1996 Issue date: Jul 14, 1998 Inventors: Marlene A. Jacobson, Richard Norton, Prasun K. Chakravarty Assignee: Merck & Co., Inc.

U.S. Classification 514/293; 514/294; 514/359; 514/461

International Classification A61K 3144; A61K 3141; A61K 3134